1. The Kibbe Body Type Test | the concept wardrobe
Bevat niet: Park Ji- hu
Determine your Kibbe Body Type with this guided Kibbe Body Type test.
2. The 13 Kibbe Body Types & Their Clothing Lines - the concept wardrobe
Bevat niet: Park Ji- hu
The Kibbe Body Types are an array of 13 style or image types based on the overall proportions of one's bone structure, body flesh and facial features.
3. Deciphering the Methylation Landscape in Breast Cancer - NCBI
2 apr 2021 · Breast cancer (BrCa) is characterized by aberrant DNA methylation. We leveraged high-throughput methylation data from BrCa and normal breast ...
Breast cancer (BrCa) is characterized by aberrant DNA methylation. We leveraged high-throughput methylation data from BrCa and normal breast tissues and identified 11,176 to 27,786 differentially methylated genes (DMGs) against clinically relevant ...
4. Classification of IDH wild-type glioblastoma tumorspheres into low
9 aug 2023 · Glioblastoma (GBM), one of the most lethal tumors, exhibits a highly infiltrative phenotype. Here, we identified transcription factors (TFs) ...
Glioblastoma (GBM), one of the most lethal tumors, exhibits a highly infiltrative phenotype. Here, we identified transcription factors (TFs) that collectively modulate invasion-related genes in GBM. The invasiveness of tumorspheres (TSs) were quantified using collagen-based 3D invasion assays. TF activities were quantified by enrichment analysis using GBM transcriptome, and confirmed by cell-magnified analysis of proteome imaging. Invasion-associated TFs were knocked down using siRNA or shRNA, and TSs were orthotopically implanted into mice. After classifying 23 patient-derived GBM TSs into low- and high-invasion groups, we identified active TFs in each group—PCBP1 for low invasion, and STAT3 and SRF for high invasion. Knockdown of these TFs reversed the phenotype and invasion-associated-marker expression of GBM TSs. Notably, MRI revealed consistent patterns of invasiveness between TSs and the originating tumors, with an association between high invasiveness and poor prognosis. Compared to controls, mice implanted with STAT3- or SRF-downregulated GBM TSs showed reduced normal tissue infiltration and tumor growth, and prolonged survival, indicating a therapeutic response. Our integrative transcriptome analysis revealed three invasion-associated TFs in GBM. Based on the relationship among the transcriptional program, invasive phenotype, and prognosis, we suggest these TFs as potential targets for GBM therapy.
5. David Kibbe body type test - Olga Brylińska
Bevat niet: Park Ji- hu
David Kibbe body type test – Olga Brylińska Image Consultant
6. Julie Ann Sosa, MD, MA, FACS, MAMSE, FSSO - Surgical Oncology
... Hu MI, Zafereo M, Sosa JA, Grubbs EG| 2024-07-26 | PubMed. Promoting Female Surgeons Through Structured Award Nominations. Trang K, Stephens CQ, Flanagan C ...
The Multi-Institutional Medullary Thyroid Cancer Collaborative Registry: Can a Rare Tumor Registry Accurately Represent the Real-World Patient Population?
7. DNA methylation in cell plasticity and malignant transformation in liver ...
... (Hu and Monga 2021, Michalopoulos and Bhushan 2021). The entire mechanism ... Park CK, Cho JW, Park YM and Jung G (2008). “Epigenetic changes induced by ...
The liver possesses extraordinary regenerative capacity mainly attributable to the ability of hepatocytes (HCs) and biliary epithelial cells (BECs) to self-replicate. This ability is left over from their bipotent parent cell, the hepatoblast, during ...
8. Duke Clinical and Translational Science Award (CTSA) Publications
... Hu R, Golla V, Harris-Gersten M. Financial Health of People ... Heterogeneity of Treatment Effects Among Patients With Type 2 Diabetes and Elevated Body ...
The Duke Clinical and Translational Science Institute (CTSI) is part of the Clinical and Translational Science Award (CTSA) program funded by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) (Grant Number UL1 TR002553, KL2 TR002554, or TL1 TR002555). The content of this website is solely the responsibility of CTSI and does not necessarily represent the official views of the NIH.
9. Genetic Delivery and Gene Therapy in Pulmonary Hypertension - MDPI
Amongst those genes is the bone morphogenetic protein receptor type 2 gene (BMPR2), a member of the transforming growth factor-β (TGF‑β) superfamily, which ...
Pulmonary hypertension (PH) is a progressive complex fatal disease of multiple etiologies. Hyperproliferation and resistance to apoptosis of vascular cells of intimal, medial, and adventitial layers of pulmonary vessels trigger excessive pulmonary vascular remodeling and vasoconstriction in the course of pulmonary arterial hypertension (PAH), a subgroup of PH. Multiple gene mutation/s or dysregulated gene expression contribute to the pathogenesis of PAH by endorsing the proliferation and promoting the resistance to apoptosis of pulmonary vascular cells. Given the vital role of these cells in PAH progression, the development of safe and efficient-gene therapeutic approaches that lead to restoration or down-regulation of gene expression, generally involved in the etiology of the disease is the need of the hour. Currently, none of the FDA-approved drugs provides a cure against PH, hence innovative tools may offer a novel treatment paradigm for this progressive and lethal disorder by silencing pathological genes, expressing therapeutic proteins, or through gene-editing applications. Here, we review the effectiveness and limitations of the presently available gene therapy approaches for PH. We provide a brief survey of commonly existing and currently applicable gene transfer methods for pulmonary vascular cells in vitro and describe some more recent developments for gene delivery existing in the field of PH in vivo.
10. William Greenleaf - Stanford Profiles
William Greenleaf is a Professor in the Genetics Department at Stanford University School of Medicine, with a courtesy appointment in the Applied Physics ...
William Greenleaf is part of Stanford Profiles, official site for faculty, postdocs, students and staff information (Expertise, Bio, Research, Publications, and more). The site facilitates research and collaboration in academic endeavors.
11. Publications - The Institute of Cancer Research, London
Hu, J.J. John, E.M. Li, C.I. Nathanson, K. Nemesure, B. Olopade, O.I. Pal ... Park, S.K. Park-Simon, T.-. Patel, A.V. Presneau, N. Pylkäs, K. Rack, B ...
Sun, X. Verma, S.P. Jia, G. Wang, X. Ping, J. Guo, X. Shu, X.-. Chen, J. Derkach, A. Cai, Q. Liang, X. Long, J. Offit, K. Oh, J.H. Reiner, A.S. Watt, G.P. Woods, M. Yang, Y. Ambrosone, C.B. Ambs, S. Chen, Y. Concannon, P. Garcia-Closas, M. Gu, J. Haiman, C.A. Hu, J.J. Huo, D. John, E.M. Knight, J.A. Li, C.I. Lynch, C.F. Mellemkjær, L. Nathanson, K.L. Nemesure, B. Olopade, O.I. Olshan, A.F. Pal, T....
12. DNA methylation aging clocks: challenges and recommendations
25 nov 2019 · ... types in the body, or pan-tissue changes [62]. Strong outlier ... Zheng Y, Joyce BT, Colicino E, Liu L, Zhang W, Dai Q, Shrubsole MJ, Kibbe WA, ...
Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure subject age. These clocks are acknowledged as a highly accurate molecular correlate of chronological age in humans and other vertebrates. Also, extensive research is aimed at their potential to quantify biological aging rates and test longevity or rejuvenating interventions. Here, we discuss key challenges to understand clock mechanisms and biomarker utility. This requires dissecting the drivers and regulators of age-related changes in single-cell, tissue- and disease-specific models, as well as exploring other epigenomic marks, longitudinal and diverse population studies, and non-human models. We also highlight important ethical issues in forensic age determination and predicting the trajectory of biological aging in an individual.
13. Publications - Sternberg Lab - Caltech
bioRXiv doi: https://doi.org/10.1101/2022.08.31.506045. Chai CM, Torkashavand M, Seyedolmohadesin M, Park H, Venkatachalam V, Sternberg PW. ... Hu PJ, Sternberg ...
Sternberg Lab Homepage / Publications
14. [PDF] Handbook of Pharmaceutical Excipients
... Kibbe. Wilkes University. Wilkes-Barre, PA, USA. William J Lambert. Eisai Inc. Research Triangle Park ... type II. 2-Hydroxyethyl-b-cyclodextrin. 2-Hydroxypropyl- ...
15. Michael Criqui - UCSD Profiles - University of California San Diego
McDermott MM, Martens CR, Domanchuk KJ, Zhang D, Peek CB, Criqui MH, Ferrucci L, Greenland P, Guralnik JM, Ho KJ, Kibbe ... JI, Psaty BM, Kathiresan S ...
Michael Criqui's profile, publications, research topics, and co-authors
16. [PDF] Identification of a DNA methylation signature in CD133+ liver cancer ...
6 feb 2014 · bind to type I and type II receptors. Upon ligand binding, the type ... Park, W.S., and Park, C.K. (2005). Promoter methylation of E ...